Familial Mediterranean Fever (FMF)
Familial Mediterranean Fever (FMF) is a genetic disease affecting people of Mediterranean or Middle Eastern descent and is also seen in populations of Jews, Turks, and Armenians.
Signs and symptoms
The disease is characterised by recurrent fever with abdominal, one-sided chest and joint pain.
Approximately 90% of patients experience abdominal pain, joint pain occurs in 50-60% of patients, and chest pain occurs in 20-40%.
Because of the intermittent and changing nature of symptoms, diagnosis involves examination and blood tests during an attack, or episode of illness, and a repeat of the blood tests when symptoms disappear.
Generally, these tests are positive during an attack and return to normal post attack. International classification criteria are used to help recognise FMF.